Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.1
USERS' SCORE
Good
Based on 82 Reviews
8
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Quercetin
800 mg
**
Bromelain (2,400 GDU/g)
165 mg
**
Top Medical Research Studies
9
We explored how quercetin, a natural compound, may help alleviate symptoms of systemic lupus erythematosus (SLE), an autoimmune disorder. Our study observed that quercetin reduced kidney damage and swelling in the lymph nodes of lupus-affected mice. It appeared to lower the number of certain T cells that drive the disease and promoted cell death in aged immune cells. By influencing key pathways, quercetin showed potential as a therapy for SLE, offering hope in tackling this complex condition.
Read More
9
We explored the effects of quercetin, a flavonoid, on rheumatoid arthritis through a well-structured study involving collagen-induced arthritis models in rats. Quercetin was administered for four weeks, and various assessments were conducted to evaluate its impact on inflammation and joint health.
Our findings revealed that quercetin significantly reduces joint inflammation and enhances metabolic function, mainly by inhibiting the JAK1/STAT3/HIF-1α signaling pathway. This suggests that quercetin could be a promising treatment option for mitigating symptoms of rheumatoid arthritis.
Our findings revealed that quercetin significantly reduces joint inflammation and enhances metabolic function, mainly by inhibiting the JAK1/STAT3/HIF-1α signaling pathway. This suggests that quercetin could be a promising treatment option for mitigating symptoms of rheumatoid arthritis.
Read More
8
We investigated how quercetin can help protect kidneys from damage caused by diabetes in rats. Our study involved forty male Wistar rats divided into different groups to compare the effects of quercetin treatment before and after diabetes was induced.
We found that quercetin significantly reduced kidney dysfunction symptoms and oxidative stress markers compared to untreated diabetic rats. This improvement linked to quercetin's ability to enhance antioxidant defenses and disrupt harmful signaling pathways. However, we observed that pretreatment with quercetin was more effective than post-treatment, suggesting timing matters in its effectiveness.
We found that quercetin significantly reduced kidney dysfunction symptoms and oxidative stress markers compared to untreated diabetic rats. This improvement linked to quercetin's ability to enhance antioxidant defenses and disrupt harmful signaling pathways. However, we observed that pretreatment with quercetin was more effective than post-treatment, suggesting timing matters in its effectiveness.
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Most Useful Reviews
9
Miracle cure
122 people found this helpful
We took Quercetin for immune support, and it unexpectedly alleviated my mother’s leg pain. It also helped with sleep and excessive sweating. I plan to keep ordering more!
Read More
9
Asthma and rhinitis
106 people found this helpful
Now Foods’ Quercetin with Bromelain has remarkably improved my asthma and rhinitis. I recommend it to anyone struggling with respiratory issues!
Read More
9
Remarkable improvement
51 people found this helpful
I was doubtful, but Quercetin has significantly reduced my husband's severe hay fever. We managed with only a minimal supply this spring compared to previous years.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.1
- All Researches
9
We explored how quercetin, a natural compound, may help alleviate symptoms of systemic lupus erythematosus (SLE), an autoimmune disorder. Our study observed that quercetin reduced kidney damage and swelling in the lymph nodes of lupus-affected mice. It appeared to lower the number of certain T cells that drive the disease and promoted cell death in aged immune cells. By influencing key pathways, quercetin showed potential as a therapy for SLE, offering hope in tackling this complex condition.
Read More
9
We explored the effects of quercetin, a flavonoid, on rheumatoid arthritis through a well-structured study involving collagen-induced arthritis models in rats. Quercetin was administered for four weeks, and various assessments were conducted to evaluate its impact on inflammation and joint health.
Our findings revealed that quercetin significantly reduces joint inflammation and enhances metabolic function, mainly by inhibiting the JAK1/STAT3/HIF-1α signaling pathway. This suggests that quercetin could be a promising treatment option for mitigating symptoms of rheumatoid arthritis.
Our findings revealed that quercetin significantly reduces joint inflammation and enhances metabolic function, mainly by inhibiting the JAK1/STAT3/HIF-1α signaling pathway. This suggests that quercetin could be a promising treatment option for mitigating symptoms of rheumatoid arthritis.
Read More
9
We explored how Sendeng-4, a traditional Mongolian medicine, can ease rheumatoid arthritis (RA). By using advanced methods to analyze its active components, we identified key phytochemicals and mapped their effects on biological pathways.
After testing on a rat model of RA, we observed that Sendeng-4 significantly reduces inflammation and arthritis symptoms, particularly through the PI3K-Akt signaling pathway. Overall, this study reveals Sendeng-4's potential benefits in treating RA and encourages further research into traditional remedies.
After testing on a rat model of RA, we observed that Sendeng-4 significantly reduces inflammation and arthritis symptoms, particularly through the PI3K-Akt signaling pathway. Overall, this study reveals Sendeng-4's potential benefits in treating RA and encourages further research into traditional remedies.
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9
Quercetin liposomes aid diabetes therapy
We observed that a new form of quercetin, delivered in lipid nanoparticles, can help alleviate diabetes symptoms in rats. This improved bioavailable quercetin significantly reduced blood glucose levels and lowered pancreatic oxidative stress and inflammation.
It also enhanced autophagy while reducing endoplasmic reticulum stress markers. However, when combined with an autophagy inhibitor, the positive effects disappeared, indicating the importance of autophagy in quercetin’s benefits. Overall, this study highlights the potential of quercetin liposomes in managing type 1 diabetes.
It also enhanced autophagy while reducing endoplasmic reticulum stress markers. However, when combined with an autophagy inhibitor, the positive effects disappeared, indicating the importance of autophagy in quercetin’s benefits. Overall, this study highlights the potential of quercetin liposomes in managing type 1 diabetes.
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8
Quercetin shows promise for RA treatment
We examined the active components in the Additive Sishen Decoction (ASSD), a traditional Chinese medicine for rheumatoid arthritis (RA). Our findings revealed that key ingredients—quercetin, kaempferol, and luteolin—play a significant role in reducing inflammation through specific pathways.
These ingredients inhibit proinflammatory factors by affecting glucose metabolism in macrophages. We employed protein interaction networks and molecular simulations to clarify their mechanisms, showing that quercetin contributes significantly to ASSD’s therapeutic effects.
Overall, we established that quercetin can be a valuable aid in managing RA symptoms.
These ingredients inhibit proinflammatory factors by affecting glucose metabolism in macrophages. We employed protein interaction networks and molecular simulations to clarify their mechanisms, showing that quercetin contributes significantly to ASSD’s therapeutic effects.
Overall, we established that quercetin can be a valuable aid in managing RA symptoms.
Read More
User Reviews
USERS' SCORE
Good
Based on 82 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Miracle cure
122 people found this helpful
We took Quercetin for immune support, and it unexpectedly alleviated my mother’s leg pain. It also helped with sleep and excessive sweating. I plan to keep ordering more!
Read More
9
Asthma and rhinitis
106 people found this helpful
Now Foods’ Quercetin with Bromelain has remarkably improved my asthma and rhinitis. I recommend it to anyone struggling with respiratory issues!
Read More
9
Remarkable improvement
51 people found this helpful
I was doubtful, but Quercetin has significantly reduced my husband's severe hay fever. We managed with only a minimal supply this spring compared to previous years.
Read More
9
Immunity boost
43 people found this helpful
I was preparing for summer cleansing but fell ill with COVID-19, severely affecting my respiratory system. I have been taking Quercetin, and I believe it aids my recovery without side effects. My digestion is good, my immunity feels stronger, and my joints hurt less. I will certainly reorder!
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9
Mild COVID symptoms
41 people found this helpful
After reading about Quercetin with Bromelain, I started taking it during my mild COVID-19 experience. I feel it helped support my immune system against the virus. I also took other supplements and recovered quickly. I highly recommend Quercetin for similar issues.
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Frequently Asked Questions
9
Reduced allergies
11 people found this helpful
Amazing! This product has been incredibly helpful for my autoimmune disorder, along with eczema and digestive issues. By adding zinc, L-glutamine, and glucosamine, I’ve almost achieved perfect relief from chronic pain. I truly hope this helps you as well.
9
Allergy relief
5 people found this helpful
I purchased Quercetin with Bromelain for my allergy to blooms, which are prevalent in Sochi. Pharmacy medicines were ineffective, but after taking these products, my symptoms improved daily, and my allergy symptoms disappeared within a week. I can now breathe freely, and I am very grateful.
9
Helped with hives
4 people found this helpful
This is my fifth order over two years. I experienced severe hives and tried various medications without success until I discovered Quercetin. After using it, my symptoms stopped, and it effectively managed my autoimmune disorder. I feel much relief when I take it, especially during flare-ups.
9
Asthma and rhinitis
106 people found this helpful
Now Foods’ Quercetin with Bromelain has remarkably improved my asthma and rhinitis. I recommend it to anyone struggling with respiratory issues!
9
Remarkable improvement
51 people found this helpful
I was doubtful, but Quercetin has significantly reduced my husband's severe hay fever. We managed with only a minimal supply this spring compared to previous years.
9
Improved sleep
8 people found this helpful
I initially took this for its antioxidant properties, but it dramatically improved my chronic rhinitis that had plagued me for years. I can now breathe through my nose while sleeping, enhancing my sleep quality. I’m very grateful for this effect.
9
Cough resolution
6 people found this helpful
I have a chronic cough due to my love for hookah, and I had given up hope of relief. After taking this drug for over two weeks, my cough has disappeared. It exceeded my expectations and has improved my situation remarkably.
9
Miracle cure
122 people found this helpful
We took Quercetin for immune support, and it unexpectedly alleviated my mother’s leg pain. It also helped with sleep and excessive sweating. I plan to keep ordering more!
9
Pain relief noted
4 people found this helpful
I started taking this for my gastroesophageal reflux disease and noticed the inflammation pain subsiding within minutes. I was surprised that a supplement could be so effective. Now, I prefer relying on supplements over medication for managing my symptoms, which may relate to my autoimmune disorder.
9
Allergy relief
1 people found this helpful
Quercetin should be taken with bromelain or vitamin C for better absorption. I ordered it as fine dust levels rose, and I noticed my allergy symptoms improved. This product worked better for me than other supplements I've tried. I trust its quality and ingredients.
9
Mild COVID symptoms
41 people found this helpful
After reading about Quercetin with Bromelain, I started taking it during my mild COVID-19 experience. I feel it helped support my immune system against the virus. I also took other supplements and recovered quickly. I highly recommend Quercetin for similar issues.
9
Nutritional support
9 people found this helpful
After a long delay, I tried this bromelain and quercetin duo as recommended by an endocrinologist. It’s excellent for autoimmune disorders, as it aids food absorption and reduces inflammation. I recommend it confidently.
9
We explored the effects of quercetin, a flavonoid, on rheumatoid arthritis through a well-structured study involving collagen-induced arthritis models in rats. Quercetin was administered for four weeks, and various assessments were conducted to evaluate its impact on inflammation and joint health.
Our findings revealed that quercetin significantly reduces joint inflammation and enhances metabolic function, mainly by inhibiting the JAK1/STAT3/HIF-1α signaling pathway. This suggests that quercetin could be a promising treatment option for mitigating symptoms of rheumatoid arthritis.
Our findings revealed that quercetin significantly reduces joint inflammation and enhances metabolic function, mainly by inhibiting the JAK1/STAT3/HIF-1α signaling pathway. This suggests that quercetin could be a promising treatment option for mitigating symptoms of rheumatoid arthritis.
9
We explored how quercetin, a natural compound, may help alleviate symptoms of systemic lupus erythematosus (SLE), an autoimmune disorder. Our study observed that quercetin reduced kidney damage and swelling in the lymph nodes of lupus-affected mice. It appeared to lower the number of certain T cells that drive the disease and promoted cell death in aged immune cells. By influencing key pathways, quercetin showed potential as a therapy for SLE, offering hope in tackling this complex condition.
8
Quercetin combined with chondroitin sulfate
We examined how quercetin interacts with chondroitin sulfate to potentially alleviate rheumatoid arthritis, a challenging autoimmune disorder linked to bacterial aggressors like Proteus mirabilis. This study utilized both in vitro and in vivo methods to identify their combined effects.
The results indicated that these compounds could reduce inflammation and oxidative stress while showing promising antibacterial properties. Zebrafish treated with the combination exhibited better survival rates under bacterial stress and showed significant metabolic improvements. Overall, it appears that quercetin and chondroitin sulfate might be valuable in managing this condition, but further research is needed to fully understand their benefits.
The results indicated that these compounds could reduce inflammation and oxidative stress while showing promising antibacterial properties. Zebrafish treated with the combination exhibited better survival rates under bacterial stress and showed significant metabolic improvements. Overall, it appears that quercetin and chondroitin sulfate might be valuable in managing this condition, but further research is needed to fully understand their benefits.
8
Quercetin shows promise for RA treatment
We examined the active components in the Additive Sishen Decoction (ASSD), a traditional Chinese medicine for rheumatoid arthritis (RA). Our findings revealed that key ingredients—quercetin, kaempferol, and luteolin—play a significant role in reducing inflammation through specific pathways.
These ingredients inhibit proinflammatory factors by affecting glucose metabolism in macrophages. We employed protein interaction networks and molecular simulations to clarify their mechanisms, showing that quercetin contributes significantly to ASSD’s therapeutic effects.
Overall, we established that quercetin can be a valuable aid in managing RA symptoms.
These ingredients inhibit proinflammatory factors by affecting glucose metabolism in macrophages. We employed protein interaction networks and molecular simulations to clarify their mechanisms, showing that quercetin contributes significantly to ASSD’s therapeutic effects.
Overall, we established that quercetin can be a valuable aid in managing RA symptoms.
References
- Ren J, Liu Z, Qi X, Meng X, Guo L, et al. Active Ingredients and Potential Mechanism of Additive Sishen Decoction in Treating Rheumatoid Arthritis with Network Pharmacology and Molecular Dynamics Simulation and Experimental Verification. Drug Des Devel Ther. 2025;19:405. doi:10.2147/DDDT.S489323
- Yang J, Yang H, Wang F, Dai Y, Deng Y, et al. Bioinformatics identification based on causal association inference using multi-omics reveals the underlying mechanism of Gui-Zhi-Shao-Yao-Zhi-Mu decoction in modulating rheumatoid arthritis. Phytomedicine. 2025;136:156332. doi:10.1016/j.phymed.2024.156332
- Zhendong Y, Changjun C, Haocheng H, Qibin L, Dailing C, et al. Regulation of macrophage polarization and pyroptosis by 4-methylcatechol alleviates collagen-induced arthritis via Nrf2/HO-1 and NF-κB/NLRP3 signaling pathways. Int Immunopharmacol. 2025;146:113855. doi:10.1016/j.intimp.2024.113855
- Priya PS, Murugan R, Srileka R, Ramya Ranjan Nayak SP, Margesan T, et al. Synergistic defense: Quercetin and chondroitin sulfate combat bacterial trigger of rheumatoid arthritis, Proteus mirabilis through in-vitro and in-vivo mechanisms. Microb Pathog. 2024;197:107086. doi:10.1016/j.micpath.2024.107086
- Xiong F, Shen K, Long D, Zhou S, Ruan P, et al. Quercetin ameliorates lupus symptoms by promoting the apoptosis of senescent Tfh cells via the Bcl-2 pathway. Immun Ageing. 2024;21:69. doi:10.1186/s12979-024-00474-9
- Karnam S, Jindal AB, Paul AT. Quality by design-based optimization of teriflunomide and quercetin combinational topical transferosomes for the treatment of rheumatoid arthritis. Int J Pharm. 2024;666:124829. doi:10.1016/j.ijpharm.2024.124829
- Zhang F, Zhang Y, Zhou J, Cai Y, Li Z, et al. Metabolic effects of quercetin on inflammatory and autoimmune responses in rheumatoid arthritis are mediated through the inhibition of JAK1/STAT3/HIF-1α signaling. Mol Med. 2024;30:170. doi:10.1186/s10020-024-00929-1
- Wu Z, Hu J, Li Y, Yao X, Ouyang S, et al. Assessment of renal pathophysiological processes and protective effect of quercetin on contrast-induced acute kidney injury in type 1 diabetic mice using diffusion tensor imaging. Redox Rep. 2024;29:2398380. doi:10.1080/13510002.2024.2398380
- Guo X, Wu W, Ran Q, Wang L, Li Y, et al. Exploring the pharmacological mechanisms of the flower of Rhododendron molle in rheumatoid arthritis rats based on metabolomics integrated network pharmacology. J Ethnopharmacol. 2024;334:118524. doi:10.1016/j.jep.2024.118524
- Pei C, Yu J, Wang G, Jia YR, Shi X, et al. Exploring the mechanism of Sendeng-4 against rheumacid arthritis through integrated serum pharmacochemistry, transcriptomics, and network pharmacology. Biomed Chromatogr. 2024;38:e5893. doi:10.1002/bmc.5893
- Zhou F, Guo YX, Gao R, Ji XY, Tang YX, et al. Quercetin regulates dendritic cell activation by targeting STAT4 in the treatment of experimental autoimmune encephalomyelitis. Toxicol Appl Pharmacol. 2024;488:116980. doi:10.1016/j.taap.2024.116980
- Hossein A, Firouzeh G, Zeinab K, Gholamreza D. Quercetin prevents kidney against diabetes mellitus (type 1) in rats by inhibiting TGF-β/apelin gene expression. Mol Biol Rep. 2024;51:677. doi:10.1007/s11033-024-09617-z
- Hou Y, Chen C, Li Z, Wu J, Lyu S, et al. Protective effect of quercetin against macrophage-mediated hepatocyte injury via anti-inflammation, anti-apoptosis and inhibition of ferroptosis. Autoimmunity. 2024;57:2350202. doi:10.1080/08916934.2024.2350202
- Li X, Wang X, Qu X, Shi N, Li Q, et al. Microenvironmental Enzyme-Responsive Methotrexate Modified Quercetin Micelles for the Treatment of Rheumatoid Arthritis. Int J Nanomedicine. 2024;19:3259. doi:10.2147/IJN.S457004
- Chen J, Huang C, Li M. [ granule inhibits podocyte autophagy in systemic lupus erythematosus: a network pharmacology and clinical study]. Nan Fang Yi Ke Da Xue Xue Bao. 2024;44:465. doi:10.12122/j.issn.1673-4254.2024.03.07
- Khater SI, El-Emam MMA, Abdellatif H, Mostafa M, Khamis T, et al. Lipid nanoparticles of quercetin (QU-Lip) alleviated pancreatic microenvironment in diabetic male rats: The interplay between oxidative stress - unfolded protein response (UPR) - autophagy, and their regulatory miRNA. Life Sci. 2024;344:122546. doi:10.1016/j.lfs.2024.122546
